Eaton's reagent

Eaton's reagent
Names
Other names
Phosphorus pentoxide-methanesulfonic acid
Identifiers
ECHA InfoCard 100.204.349
EC Number
  • 679-375-3
Properties
hydrolyzes
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

Eaton's reagent[1] (10 wt% phosphorus pentoxide solution in methanesulfonic acid) is used as an alternative to polyphosphoric acid in chemical synthesis to promote acylation reactions.

References

  1. ^ Eaton, P. E.; Carlson, G. R.; Lee, J. T. (1973). "Phosphorus pentoxide-methanesulfonic acid. Convenient alternative to polyphosphoric acid". J. Org. Chem. 38 (23): 4071. doi:10.1021/jo00987a028.


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